What we talk about
From technical deep-dives to philosophical debates, here's where the magic happens.
Imaging Methods
Compare EM, ExM, X-ray, and more. Talk about pipelines, discuss method shortcomings, or nerd out over voxel sizes
What we discuss:
- FIB-SEM vs. sSEM: pros & cons?
- Automated sectioning protocols and throughput
- Voxel size optimization for different tissues
- Method shortcomings and workarounds
Recent discussion:
"FIB-SEM vs. sSEM: pros & cons?"
Computational Neuroscience
Simulations, neuronal dynamics, storage and processing requirements for a fly's connectome
What we discuss:
- Hodgkin–Huxley vs. Integrate and Fire models
- Neural network simulations and dynamics
- Connectome data storage solutions
- Processing pipeline optimization
Recent discussion:
"What model is better, Hodgkin–Huxley or Integrate and Fire?"
Biology & Anatomy
Species-specific neuro-anatomy: fly, mouse, human. Chemical composition of neurons, tissue preservation, etc.
What we discuss:
- Cross-species neuroanatomical comparisons
- Neuronal cytoplasm composition
- Tissue preservation techniques
- Synaptic structure variations
Recent discussion:
"What is a neuron's cytoplasm made out of?"
Philosophy & Ethics
Mind-uploading, consciousness, ethics. Thought experiments & 'what if…?' threads are fair game
What we discuss:
- Personal identity and brain replacement
- Consciousness theories and debates
- Ethics of mind uploading
- Thought experiments on neural continuity
Recent discussion:
"Can personal identity survive a destructive replacement of the brain?"
Paper Sharing & Journal Club
Post papers, pre-prints, and recorded talks. Ask for explainers or give a mini-journal-club summary
What we discuss:
- Latest MICrONS research discussions
- Neuronal plasticity paper presentations
- Pre-print reviews and summaries
- Recorded talk recommendations
Recent discussion:
"Has anyone read the new MICrONS paper? I'd like to present a paper on neuronal plasticity I really liked."
Beyond the science
We're not all work and no play. Here's where we connect as humans.
Free-form Chat
Off-topic banter, advice, memes, and questions that don't fit in any of the other categories
"Favorite brain-mapping podcasts?"
Resources Hub
Curated papers, videos, and educational materials with summaries
Hand-picked articles with summaries so you can decide whether to dive deep.
Member Roles
Claim your member badge and unlock discussion privileges
Hit 🧪 to unlock the Member role and start participating in discussions.
Ready to dive in?
Whether you're interested in the technical details or the big philosophical questions, there's a conversation waiting for you.